Chest CT Appearances

Hodgkin Lymphoma CT Findings

• Enlarged lymph nodes
• Central necrosis
• Variable enhancement
• Homogeneous
• Lobulated, round masses
• Mesenteric lymph nodes encase the mesenteric vessels (“sandwich sign”)

Other Information About Hodgkin Lymphoma

Etiology:

• Unknown
• Associated with Epstein-Barr virus
• More common in patients with HIV and other immunocompromising conditions
• Familial history of HL increases the risk

Epidemiology:

• More common in males
• Bimodal: typically presents between ages 20-40 or after age 65

Presentation:

• Palpable mass
• Fever
• Malaise
• Anorexia
• Weight loss
• Pruritus
• Night sweats
• Cough
• Dyspnea

Prognosis:

• The 5-year relative survival rate for all Hodgkin Lymphoma is:
  • Localized: 93%
  • Regional: 95%
  • Distant: 84%
  • All SEER stages combined: 89%

Related Lectures:
CT of Anterior Mediastinal Masses: Core Concepts - Part 3