Small Bowel CT Appearances

Zollinger-Ellison Syndrome (ZES) CT Findings

• Thickened rugal folds
• Multiple gastric nodules
• Gastrinoma (usually < 1 cm) is most often located in the gastrinoma triangle

Other Information About Zollinger-Ellison Syndrome (ZES)

Etiology:

• Caused by gastrinomas
• Associated with MEN1

Epidemiology:

• Typically present in the 4th-6th decades of life

Presentation:

• Diarrhea
• Abdominal pain (burning sensation)
• Acid reflux
• Heartburn
• Nausea and/or vomiting
• Weight loss

Prognosis:

• ZES-causing gastrinomas can be benign or malignant
• If malignant and treated, the 5-year survival rate can be over 90%