Small Bowel CT Appearances

Castleman Disease CT Findings

• Usually classified and unicentric or multicentric
  • Unicentric: a solitary, noninvasive mass
  • Multicentric: a dominant mass with involvement of surrounding structures
• Hyperdense to isodense lesions common
• Enlarged, hypervascular appearance of involved lymph nodes

Other Information About Castleman Disease

Etiology:

• Unknown
• Linked to HIV

Epidemiology:

• Rare
• Affects males and females equally
• Age range for Castleman disease is broad, typically from the 4th-7th decades of life

Presentation:

• Unicentric Castleman Disease (UCD) is asymptomatic
• Multicentric Castleman Disease (MCD) may present with fever, night sweats, weight loss, and fatigue

Prognosis:

• Prognosis after surgical resection is good