Musculoskeletal CT Appearances
Lymphoma of Bone CT Findings
- Typically involves the long bones
- Long bone with a solitary, well defined lytic lesion at the end
- “Moth eaten” destruction
- Multiple small rarefactions parallel to long axis of bone (permeative destruction)
- Aggressive periosteal reaction
- Extra-osseous soft tissue mass
- Cortical breakthrough may be present in more advanced cases
- May have lymph node involvement
- CT findings are not specific for primary lymphoma of bone
Other Information About Lymphoma of Bone
Etiology:
- Unknown
Epidemiology:
- Very rare
- Typically presents between ages 45 and 60
- More common in males
Presentation:
- Bone pain
- Palpable mass
- Bone fracture
- Fatigue
- Fever
- Night sweats
- Weight loss
Prognosis:
- The 5-year relative survival rate is about 58% and increases significantly with treatment
- Since lymphoma of bone is rare, the survival rate is unknown
Related Pearls: Bone Tumors