Musculoskeletal CT Appearances

Paget's Disease CT Findings

• Lytic:
  • Osteolysis with resorption
  • Osteolysis has sharp, leading edge (“blade of grass” or “candle flame”)
• Mixed:
  • Cortical thickening
  • Osseous expansion
  • Coarsening and thickening of trabeculae
• Sclerotic:
  • Osteosclerosis
  • Fatigue fractures and bowing deformities
• Usually involves multiple bones

Other Information About Paget's Disease

Etiology:

• Unknown
• Familial history

Epidemiology:

• Typically presents over age 50
• More common in people of northern European heritage
• Slightly more common in males

Presentation:

• Typically asymptomatic
• Bone or joint pain
• Bowing of the long bones
• Bones that fracture easily

Prognosis:

• There is no cure for Paget’s disease but it can be managed

Related Pearls: Paget's Disease