Musculoskeletal CT Appearances

Multiple Myeloma CT Findings

• Osteolytic bone destruction (>5 mm) in one or more locations
• 70-80% of patients have “punched-out” osteolytic lesions (small, low density) with positive HU values
• Soft tissue masses not uncommon
• Can appear anywhere in the skeletal system, most commonly in the vertebrae, ribs, skull and shoulder