Rhabdomyosarcoma, Masticator Space

12-year-old female with gradual onset of the odynophagia. There is a large, partly circumscribed, heterogeneous, T1 slightly hypointense to skeletal muscle, T2/STIR hyperintense mass centered within the right masticator space. The mass enhances solidly and extends to the skull base on the right with involvement of Meckels cave via the foramen ovale. This is a case of rhabdomyosarcoma which is a malignant tumor with skeletal muscle cell morphology. Rhabdomyosarcomatous are the most common soft tissue tumor in children accounting for approximately 25% of all pediatric soft tissue sarcomas. The majority occur in patients under 10 years of age. There is a slight male predilection. Clinical presentation depends on the tumor location. Associations include neurofibromatosis type I, Beckwith Weidman syndrome, and Li-Fraumeni syndrome. Treatment is with a combination of surgery, chemotherapy, and radiation.