Myxofibrosarcoma grade 3

45-year-old male with a slowly enlarging left thigh mass. There is a well-circumscribed solid appearing T1 mildly heterogeneous but predominantly isointense, T2/STIR heterogeneously hyperintense, centrally necrotic peripherally enhancing mass in the mid medial left thigh. A small plane of fat is maintained between the lateralmost lesion boundary and the cortical margin of the left femoral diaphysis at that site. There is mild perilesional edema. A myxoid tumor of the soft tissues was favored. This lesion was found to be a grade 3 myxofibrosarcoma. Imaging features of myxoid soft tissue tumors include high signal intensity characteristics on T2 weighted images because of high water content. Lesions range from benign to malignant entities. Some of the benign etiologies include intramuscular myxoma, synovial cyst, bursa, ganglion and benign peripheral nerve sheath tumor. Malignant etiologies include myxoid leiomyosarcoma, myxoid liposarcoma, myxoid chondrosarcoma and myxoid fibrosarcoma. Treatment for the malignant subtypes is usually with preoperative chemoradiation therapy followed by gross total resection.