Imaging Pearls ❯ Pancreas ❯ Perfusion
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- “ Compared to the control population, significant decreases in perfusion values were observed in all pancreatic pathologies under study, except in neuroendocrine tumors. Perfusion CT values can be used as an additional parameter to differentiate pancreatic pathologies.”
Tissue Perfusion in Pathologies of the Pancreas: Assessment Using 128-slice Computed Tomography
Delrue L et al.
Abdom Imaging (2012) 37;595-601 - “ Blood flow and blood volume were significantly lower in acute and chronic pancreatitis compared to the control group. In the center of adenocarcinoma tumors, low blood flow and blood volume were observed, gradually increasing toward the tumor rim; perfusion values in pancreatic parenchyma adjacent to the tumor were not significantly different from the control population.”
Tissue Perfusion in Pathologies of the Pancreas: Assessment Using 128-slice Computed Tomography
Delrue L et al.
Abdom Imaging (2012) 37;595-601 - “ Blood flow and blood volume were significantly lower in acute and chronic pancreatitis compared to the control group. In the center of adenocarcinoma tumors, low blood flow and blood volume were observed, gradually increasing toward the tumor rim; perfusion values in pancreatic parenchyma adjacent to the tumor were not significantly different from the control population. In neuroendocrine tumors, significantly increased perfusion values were observed.”
Tissue Perfusion in Pathologies of the Pancreas: Assessment Using 128-slice Computed Tomography
Delrue L et al.
Abdom Imaging (2012) 37;595-601 - CT Perfusion Protocol
Non contrast CT
Contrast enhanced CT (50 cc Visipaque-320 at 5 cc/sec followed by 50 cc of saline at 5 cc/sec)
- 100 kVp
- 145 mAs
- 5 mm slice thickness
- Images acquired over 51 seconds ( 12 acquisitions every 1.5 sec, followed by four acquisitions every 4.5 seconds and 2 acquisitions with a time interval of 7.5 seconds) with 18 acquisitions