- Age usually 20-50 - 1-5% of patients with sarcoidosis affected with it occuring more commonly in woman and blacks (black-white is about 10x) - Range of CNS patterns of involvement from leptomeninges, dura mater, subarachnoid space, brain parenchyma,ventricular system, peripheral nerves
Neurosarcoidosis: Facts
- When parenchymal disease present usually in periphery of parenchyma - Key differential diagnosis usually focuses on primary vs matastatic brain tumor Case Courtesy of: Elaine Lewis MD The Reading Hospital and Medical Center Reading,Pa.
Neurosarcoidosis: CT Findings in the Brain
- Hydrocephalus - Periventricular hypoattenuation and contrast enhancement - Calcifications (calcified granulomas) - Meningeal contrast enhancement - White matter lesions - Lesions at the optic nerve or chiasm
Neurosarcoidosis: MRI Findings in the Brain
- Periventricular high-signal lesions on T2-weighted image - Multiple supratemtorial and infratentorial brain lesions - Solitary intra-axial mass - Solitary extra-axial mass - Leptomeningeal enhancement - Optic nerve enhancement
