Imaging Pearls ❯ Neuroradiology ❯ Inflammatory Disease
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- Neurosarcoidosis: Facts
- Age usually 20-50
- 1-5% of patients with sarcoidosis affected with it occuring more commonly in woman and blacks (black-white is about 10x)
- Range of CNS patterns of involvement from leptomeninges, dura mater, subarachnoid space, brain parenchyma,ventricular system, peripheral nerves - Neurosarcoidosis: Facts
- When parenchymal disease present usually in periphery of parenchyma
- Key differential diagnosis usually focuses on primary vs matastatic brain tumor
Case Courtesy of:
Elaine Lewis MD
The Reading Hospital and Medical Center
Reading,Pa. - Neurosarcoidosis: CT Findings in the Brain
- Hydrocephalus
- Periventricular hypoattenuation and contrast enhancement
- Calcifications (calcified granulomas)
- Meningeal contrast enhancement
- White matter lesions
- Lesions at the optic nerve or chiasm - Neurosarcoidosis: MRI Findings in the Brain
- Periventricular high-signal lesions on T2-weighted image
- Multiple supratemtorial and infratentorial brain lesions
- Solitary intra-axial mass
- Solitary extra-axial mass
- Leptomeningeal enhancement
- Optic nerve enhancement