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Everything you need to know about Computed Tomography (CT) & CT Scanning

Cardiac: Vasculitis Imaging Pearls - Educational Tools | CT Scanning | CT Imaging | CT Scan Protocols - CTisus
Imaging Pearls ❯ Cardiac ❯ Vasculitis

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  • “Behcet's disease (BD) is a chronic inflammatory disorder, with vasculitis underlying the pathophysiology of its multisystemic effects. Venous pathology and thrombotic complications are hallmarks of BD. However, it has been increasingly recognized that cardiac involvement and arterial complications are also important aspects of the course of the disease. Cardiac lesions include pericarditis, endocarditis, intracardiac thrombosis, myocardial infarction, endomyocardial fibrosis, and myocardial aneurysm.”
    Cardiac manifestations in Behcet's disease
    Selami Demirelli et al.
    Intractable Rare Dis Res. 2015 May; 4(2): 70–75.
  • "The morphological basis of the systemic manifestations in BD, including cardiovascular involvement, is vasculitis . More specifically, some pathologists consider perivascular structures as the main target of T lymphocyte-mediated immune reactions, and perivasculitis as an essential part of the vasculopathy in BD. The venous and arterial wall lesions attract cytokinergic and neutrophilic reactions. Activated neutrophils cause destructive effects by excessive production of superoxide anion radicals and lysosomal enzymes. Neutrophilic infiltration and advanced vascular wall destruction with aneurysm formation cause local blood flow abnormalities.”
    Cardiac manifestations in Behcet's disease
    Selami Demirelli et al.
    Intractable Rare Dis Res. 2015 May; 4(2): 70–75.
  • "Coronary aneurysms may be seen during angiography procedures in patients with BD. Some of these aneurysms are asymptomatic, whereas others manifest with acute coronary syndrome. These aneurysms are isolable, and most are evident together with coronary stenosis and are sometimes seen together with several arterial aneurysms.”
    Cardiac manifestations in Behcet's disease
    Selami Demirelli et al.
    Intractable Rare Dis Res. 2015 May; 4(2): 70–75.
  • “Behcet's disease (BD) is a multisystem vasculitis of unknown etiology, characterized by recurrent urogenital ulceration, cutaneous eruptions, uveitis, arthritis and vasculitis. Less commonly, coronary arteries are involved, with potential serious consequences.”
    PREVALENCE AND PREDICTORS OF CORONARY ARTERY DISEASE IN BEHCET'S DISEASE
    Jalaj Garg et al. 
    Journal of the American College of Cardiology
    Volume 63, Issue 12 Supplement, April 2014
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