Vascular Complications in Chronic Pancreatitis
Anil K. Agarwal, Raja Kalayarasan, Amit Javed
Chronic pancreatitis (CP) is characterized by persistent chronic inflammation that leads to permanent structural changes in the pancreas and impairment of both endocrine and exocrine functions. The CP-related vascular complications can be broadly classified into arterial and venous. Arterial complications are reported in 1.3–10% of patients with CP and pseudoaneurysm accounted for most of these arterial complications. Venous complications in CP usually manifest as splanchnic venous thrombosis. The reported prevalence of venous thrombosis in patients with CP ranges from 3 to 41.7% due to heterogeneity in the published literature, with a pooled prevalence of 11.6%. The focus is on splenic vein thrombosis, the most common venous complication in patients with CP. Clinical manifestations of CP such as pain, steatorrhea, diabetes mellitus, and weight loss remain the dominant symptom in most CP patients with splenic vein thrombosis.
Read Full Article Here: https://doi.org/10.1002/9781119570097.ch41