CT Characteristics and Pathologic Basis of Solitary Cystic Lung Cancer.
Radiology. 2019 Mar 12:181598. doi: 10.1148/radiol.2019181598. [Epub ahead of print]
Tan Y1, Gao J1, Wu C1, Zhao S1, Yu J1, Zhu R1, Zhang Q1, Wu G1, Xue X1, Wu J1.
There are increasing reports of a type of lung cancer that manifests as solitary cystic airspaces. The purpose of this case series was to identify the CT features and possible mechanisms of solitary cystic lung cancer, on the basis of CT observations and pathologic characteristics. The clinical, imaging, and pathologic data of 106 patients with solitary cystic lung cancer were collected and analyzed between January 2011 and December 2017. CT images were reviewed independently by three radiologists who were blinded to pathologic findings. Demographic data and clinical and smoking status were extracted from the medical records. The mean age was 58.8 years ± 10.6 (standard deviation) (range, 30-82 years). CT features in the 106 patients included nonuniform cystic walls in 96 (90.6%) patients, cyst septations in 62 (58.5%) patients, nodular walls in 58 (54.7%) patients, ground-glass opacity around the cyst in 53 patients (50.0%), and irregular margins in 42 (39.6%) patients. At histologic examination, the majority of cases (81 [87.1%] of 93) were adenocarcinoma. © RSNA, 2019 Online supplemental material is available for this article. See also the editorial by Mergo and Rojas in this issue.
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