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Everything you need to know about Computed Tomography (CT) & CT Scanning

MDCT of the Spleen: Pathology: Hemangioma


Hemangiomas are the most common primary tumor of the spleen with a prevalence of 0.03-14%. This is a congenital lesion arising from sinusoidal epithelium resulting from proliferation of vascular channels lined by a single layer of endothelium, most often resulting in a cavernous lesion.

Hemagiomas are variable in size ranging from a few millimeters to several centimeters. The majority are less than 4 cm, but there are reports of lesions up to 17 cm. Hemangiomas may be single or multiple as in Klippel-Trenauney-Weber syndrome.

On noncontrast CT hemangioma are either hypodense or isodense to the spleen. Following injection of intravenous contrast, these tumors may remain hypodense, but exhibit peripheral enhancement. However, the typical filling-in seen with hepatic hemangiomas is not necessarily the rule with splenic hemangiomas. These lesions tend to be well circumscribed and may contain either central punctate calcifications or peripheral curvilinear calcifications of cystic regions.

The majority of hemangiomas are asymptomatic and incidentally discovered. However, larger lesions may enlarge the spleen leading to fullness and left upper quadrant discomfort. Complications consist of spontaneous splenic rupture in 25% of cases. Kasabach-Merritt is a syndrome reported in patients with large hemangiomas. These patients develop anemia, thrombocytopenia, and coagulopathy with multiple hemangiomas throughout the body, but predominately in the lung and liver. The multiple hemangiomas can lead to massive shunting and cardiac failure. Management consists of embolization to decreased shunting and control the consumptive coagulopathy in individuals with severe Kasabach-Merritt syndrome.




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