Gastrointestinal stromal tumors (GISTs), the most common sarcoma of the gastrointestinal tract, are mesenchymal tumors that generally arise in adults with a peak incidence in the sixth decade of life. Though most frequently found in the stomach or small intestine, GISTs may develop anywhere along the gastrointestinal tract. Approximately 1 in 4 GISTs are diagnosed incidentally, with imaging playing a crucial role in their detection and characterization. Due to their often clinically insidious growth, up to 25% of patients may already have metastatic disease at the time of diagnosis. In this article, we report the case of a 67-year-old woman who was incidentally diagnosed with a duodenal GIST. We analyze the computed tomography imaging findings and correlate them with the patient's clinical features.