Bo Gao, Wendu Duan
Digit Health. 2025 Apr 13:11:20552076251325418. doi: 10.1177/20552076251325418. eCollection 2025 Jan-Dec.
Early detection, accurate diagnosis, and effective treatment of liver diseases are of paramount importance for improving patient survival rates. However, traditional methods are frequently influenced by subjective factors and technical limitations. With the rapid progress of artificial intelligence (AI) technology, its applications in the medical field, particularly in the prediction, diagnosis, and treatment of liver diseases, have drawn increasing attention. This article offers a comprehensive review of the current applications of AI in hepatology. It elaborates on how AI is utilized to predict the progression of liver diseases, diagnose various liver conditions, and assist in formulating personalized treatment plans. The article emphasizes key advancements, including the application of machine learning and deep learning algorithms. Simultaneously, it addresses the challenges and limitations within this domain. Moreover, the article pinpoints future research directions. It underscores the necessity for large-scale datasets, robust algorithms, and ethical considerations in clinical practice, which is crucial for facilitating the effective integration of AI technology and enhancing the diagnostic and therapeutic capabilities of liver diseases.