Comparison of Frontier Open-Source and Proprietary Large Language Models for Complex Diagnoses

Thomas A Buckley, Byron Crowe, Raja-Elie E Abdulnour, Adam Rodman, Arjun K Manrai

JAMA Health Forum . 2025 Mar 7;6(3):e250040. doi: 10.1001/jamahealthforum.2025.0040.

Summary

This comparative effectiveness research assesses the performance of newer open-source large language models (LLMs) with that of closed-source proprietary large LLMs.