Genomic-Based Early Detection Screening: A Literature Review of Prospective Trials and Emerging Strategies for Gastrointestinal Cancers

Eemon Tizpa, Kaveh Sharzehi, Nima Nabavizadeh

Cureus . 2024 Sep 7;16(9):e68881. doi: 10.7759/cureus.68881. eCollection 2024 Sep.

Abstract

Numerous genomic-based early detection screening tests are being developed. These tests have the potential to revolutionize current single-organ screening paradigms, especially in gastrointestinal cancers. In this review, we underscore the performance of these genomic-based early detection tests based on prospective clinical trials. Moreover, we discuss a professional advancement for gastroenterologists in the diagnostic assessment of individuals who are cancer signal positive.