AJR 2004; 182:769-775.
Ko SF, Hsieh MJ, Ng SH, Lin JW, Wan YL, Lee TY, Chen WJ, Chen MC.
Castleman's disease, also known as angiofollicular or benign giant lymph node hyperplasia, is an uncommon benign lymphoproliferative disorder [1-3]. Pathologically, two major histologic types are recognized: the hyaline-vascular type and the plasma cell type. The hyaline-vascular type (Fig. 1), accounting for approximately 90% of cases, is characterized by germinal follicles with hyalinized vessels surrounded by concentric layers of small lymphocytes with proliferative interfollicular vascular stroma.