Abstract: Diabetes mellitus is the most common multisystemic endocrine disorder. It can be complicated by several serious gastroin�testinal manifestations that can be depicted by a variety of imaging methods. This article reviews the most commonly depicted gastrointes�tinal and hepatobiliary findings in patients with diabetes mellitus. These findings include motor dysfunction, biliary stasis with cholelithiasis and emphysematous cholecystitis, and fatty infiltration of the liver and pancreas.