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Adrenal: Adrenal Myelolipoma Imaging Pearls - Learning Modules | CT Scanning | CT Imaging | CT Scan Protocols - CTisus
Imaging Pearls ❯ Adrenal ❯ Adrenal Myelolipoma
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  • “Adrenal myelolipoma is a benign tumor of varied composition of adipose tissue and myelopoietic cells, usually trilinear elements. Myelolipoma is relatively uncommon, occurring in 0.08%–0.2% of cases in autopsy series. These tumors are not hormonally active and usually are asymptomatic, unless they grow to a large size and exert mass effect or have internal hemorrhage. Very rarely, myelolipomatous foci are associated with adrenal functional disorders such as Cushing syndrome.”

    
From the Radiologic Pathology Archives: Adrenal Tumors and Tumor-like Conditions in the Adult: Radiologic-Pathologic Correlation
Grant E. Lattin, Jr et al.
RadioGraphics 2014 34:3, 805-829 
  • Myelolipoma
    - Benign
    - Nonfunctioning
    - Hematopoeitic tissue & mature adipose
    - 2-17 cm
  • Myelolipoma
    1. Change over time
    - remain stable
    - enlarge
    - get smaller
    2. Complications
    - mass effect
    - hemorrhage
  • “The CT features are characteristic. Lesions usually have a negative Hounsfield unit value owing to macroscopic fat. Because of intermixed hematopoietic tissue, the attenuation is usually higher than that of retroperitoneal fat. High-attenuation regions may be seen due to hemorrhage or calcifications.”
    CT and MR Imaging of Extrahepatic Fatty Masses of the Abdomen and Pelvis: Techniques, Diagnosis, Differential Diagnosis, and Pitfalls
    Pereira JM et al.
    RadioGraphics January 2005 vol. 25 no. 1 69-85
  • “Myelolipoma is an uncommon benign tumor composed of mature adipose cells and hematopoietic tissue. The prevalence in autopsy series is between 0.08% and 0.2% . Typically, myelolipoma arises in the adrenal gland. Extra-adrenal myelolipoma is rare and is found most commonly in the presacral and other retroperitoneal areas . Usually asymptomatic and discovered incidentally at cross-sectional imaging, myelolipoma occasionally causes discomfort due to compression or hemorrhage.”
    CT and MR Imaging of Extrahepatic Fatty Masses of the Abdomen and Pelvis: Techniques, Diagnosis, Differential Diagnosis, and Pitfalls
    Pereira JM et al.
    RadioGraphics January 2005 vol. 25 no. 1 69-85
  • Myelolipoma

    Change over time
    -remain stable
    -enlarge
    -get smaller

    Complications
    -mass effect
    -hemorrhage
  • Myelolipoma
    -Benign
    -Nonfunctioning
    -Hematopoeitic tissue & mature adipose
    -2-17 cm
  • Adrenal Lesions that Contain Fat: Differential Diagnosis
    - Adrenal Myelolipoma
    - Adrenal Adenoma
    - Adrenal Pheochromocytoma
    - Adrenal Carcinoma
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