Imaging of secretory tumors of the gastrointestinal tract.
Abdom Radiol (NY). 2017 Apr;42(4):1113-1131. doi: 10.1007/s00261-016-0976-4.
ElGuindy YM1, Javadi S2, Menias CO3, Jensen CT2, Elsamaloty H1, Elsayes KM4.
Gastrointestinal secretory tumors, or gastroenteropancreatic neuroendocrine tumors, encompass a wide array of endocrine cell tumors. The significance of these tumors lies in their ability to alter physiology through hormone production as we well as in their malignant potential. Functioning tumors may present earlier due to symptomatology; conversely, non-functioning tumors are often diagnosed late as they reach large sizes, causing symptoms secondary to local mass effect. Imaging aids in the diagnosis, staging, and prognosis and provides key information for presurgical planning. Although most of these tumors are sporadic, some are associated with important syndromes and associations, knowledge of which is critical for patient management. In this article, we provide an overview of secretory and neuroendocrine tumors of the GI tract and pancreas.