Rosai-Dorfman Disease: Manifestations Outside of the Head and Neck.
AJR Am J Roentgenol. 2017 Apr;208(4):721-732. doi: 10.2214/AJR.15.15504. Epub 2017 Jan 31.
Mar WA1, Yu JH2, Knuttinen MG3, Horowitz JM4, David O5, Wilbur A1, Menias CO3.
OBJECTIVE: Rosai-Dorfman disease (RDD) is an uncommon benign histiocytic disorder. Extranodal involvement occurs in 43% and most commonly involves the head and neck, skin, and bones. We review less common imaging findings outside the head and neck.
CONCLUSION: The imaging manifestations of RDD overlap with a variety of neoplastic and nonneoplastic conditions. Confirmation of an RDD diagnosis is based on specific histologic features. Radiologic assessment is used to rule out multifocality on initial workup and to evaluate treatment response.